Rectal Cancer

First-Line Treatment with Dostarlimab Led to Remission in All Patients with Mismatch Repair-Deficient Rectal Cancer
By Phoebe Starr
ASCO 2022 Highlights, Rectal Cancer
August 2022, Vol 13, No 4 Online Only
First-line treatment with dostarlimab-gxly (Jemperli), a PD-1 inhibitor, achieved complete responses (CRs) in 100% of a subset of patients with locally advanced mismatch repair-deficient (dMMR) rectal cancer, sparing them surgery, chemotherapy, and radiation, as of the latest follow-up.
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