ASCO

Platinum-based chemoradiation therapy (CRT) is the current standard treatment for locally advanced SCCHN, and induction docetaxel/cisplatin/5-fluorouracil (TPF) is superior to cisplatin/5-fluorouracil alone, but it has not been tested when added to concomitant therapy.

Read Article

The E1308 Trial: Reduced-Dose IMRT in HPV-Associated OPSCC After Induction Chemotherapy

ASCO 2014 – Colorectal and Head & Neck Cancer, ASCO

Conference Correspondent

In the E2399 trial, HPV+ patients with oropharyngeal squamous cell carcinoma (OPSCC) attained 2-year overall survival (OS) of 95% and progression-free survival (PFS) of 86% when treated with induction chemotherapy (IC) and 70 Gy chemoradiation.

Read Article

RTOG 0522: The KRAS Variant and Response to Cetuximab

ASCO 2014 – Colorectal and Head & Neck Cancer, ASCO

Conference Correspondent

In many cancers, KRAS mutations can predict cancer risk, unique cancer biology, and response to certain therapeutic agents. RTOG 0522 was a phase 3 trial of cisplatin/radiation ± cetuximab for patients with locally advanced SCCHN, evaluating whether KRAS mutation status would predict the response to cetuximab in these patients (Weidhaas JB, et al. ASCO 2014. Abstract 6000).

Read Article

Adjuvant Lapatinib Plus Chemoradiation in High-Risk Patients with SCCHN

ASCO 2014 – Colorectal and Head & Neck Cancer, ASCO

Conference Correspondent

Read Article

Maintenance Strategies in mCRC After First-Line Therapy

ASCO 2014 – Colorectal and Head & Neck Cancer, ASCO

Conference Correspondent

Read Article

Final Results of the CAIRO3 Study

ASCO 2014 – Colorectal and Head & Neck Cancer, ASCO

Conference Correspondent