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AUA Revises Its Guidelines for Prostate Cancer PSA Screening
By
Charles Bankhead
Prostate Cancer
,
Solid Tumors
May 2013, Vol 4, No 4
Prostate cancer screening with prostate-specific antigen (PSA) tests should focus on men aged 55 to 69 years, the group that is the most likely to benefit from screening, according to a new clinical guideline issued by the American Urological Association (AUA) at its 2013 annual meeting.
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Deviation from Clinical Guidelines Takes Toll on Ovarian Cancer Survival
By
Charles Bankhead
Ovarian Cancer
,
Personalized Medicine
,
Solid Tumors
May 2013, Vol 4, No 4
Most women with ovarian cancer receive substandard care that significantly reduces their survival odds, based on a new retrospective review of 13,000 patients that was presented at the 2013 Society of Gynecologic Oncology annual meeting.
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Novel Immunotherapy Approach Encouraging in Advanced Ovarian Cancer
By
Phoebe Starr
Ovarian Cancer
,
Solid Tumors
May 2013, Vol 4, No 4
Washington, DC—A 2-step immunotherapy approach holds promise for women with advanced recurrent ovarian cancer, a disease that has limited therapeutic options.
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HDAC Inhibitor plus PARP Inhibitor or Cisplatin Induce Apoptosis of Triple-Negative Breast Cancer Cells
By
Caroline Helwick
Breast Cancer
,
Personalized Medicine
,
Solid Tumors
March 2013, Highlights
Histone deacetylase (HDAC) inhibitors may have a future in the targeted treatment of triple-negative breast cancer, if the results of in vitro studies can be replicated clinically.
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Eribulin Plus Trastuzumab an Effective Combination
By
Caroline Helwick
Breast Cancer
,
Personalized Medicine
,
Solid Tumors
March 2013, Highlights
Eribulin mesylate (Halaven) is currently used in patients with metastatic breast cancer whose disease has progressed on other treatments, but the drug may be useful in earlier lines of therapy.
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HER2 Mutations May Become New Treatment Targets
By
Caroline Helwick
Breast Cancer
,
Personalized Medicine
,
Solid Tumors
March 2013, Highlights
Some patients who test HER2 negative by conventional tests may still benefit from anti-HER2 agents. This is the conclusion of a study that examined HER2 mutations in detail which was presented by Ron Bose, MD, PhD, Assistant Professor, Oncology Division, Department of Medicine, Washington University School of Medicine in St Louis, MO.
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Results of Immunohistochemistry and In Situ Hybridization Reliable Indicators of HER2-Positive Status
By
Susan Reckling
Breast Cancer
,
Personalized Medicine
,
Solid Tumors
March 2013, Highlights
The incidence of false-negative immunohistochemistry (IHC) is only 1% in patients with primary breast cancer, according to a prospective multicenter Canadian study presented at the meeting.
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One Year of Trastuzumab Remains the Standard of Care
By
Caroline Helwick
Breast Cancer
,
Personalized Medicine
,
Solid Tumors
March 2013, Highlights
For patients with HER2-positive early breast cancer, 1 year of treatment with trastuzumab (Herceptin) remains the standard of care, according to the HERA trial and a subanalysis of the PHARE study.
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HER2 Status Determined by Central Laboratory Testing May Be More Reliable than Routine Local Testing
By
Susan Reckling
Breast Cancer
,
Personalized Medicine
,
Solid Tumors
March 2013, Highlights
Determining HER2 status utilizing novel central laboratory testing techniques has been shown to be more reliable than routine local HER2 testing, such as immunohistochemistry or in situ hybridization.
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Targetable Pathways Revealed for Triple-Negative Breast Cancer
By
Audrey Andrews
Breast Cancer
,
Solid Tumors
March 2013, Highlights
>The molecular make-up of triple- negative breast cancer is becoming better understood, and new evidence suggests that the main biologic pathways can be targeted with drugs, according to Justin Balko, PharmD, PhD, Postdoctoral Research Fellow and Researcher, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville.
Read Article
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Home
Issues
Online First
Latest Issue
Issue Archive
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Personalized Medicine
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FDA Approvals, News & Updates
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Cholangiocarcinoma
View All Topics ›
Conference Correspondent
SABCS 2023 - HER2+ MBC
ASCO 2023 - Breast Cancer
Web Exclusives
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Videos
Interview with the Innovators
Prostate Cancer Diagnostics Monthly Minutes
Webinars
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AVBCC
Association for Value-Based Cancer Care
VBCM
Value-Based Care in Myeloma