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Articles
Articles
Cost Considerations for New Oral Therapies for Patients with Metastatic Castration Resistant Prostate Cancer (mCRPC) Previously
By
Zoe Clancy
;
Lorie A. Ellis
;
R. Scott McKenzie
;
Mekré Senbetta
March 2013, Vol 4, No 3
Background:
Two oral agents for mCRPC patients who previously received docetaxel were recently approved by the US Food and Drug Administration—abiraterone acetate plus prednisone (AA+p) and enzulatamide (EN). Phase 3 studies in this population showed median treatment duration of 8 months for AA+p1 and 8.3 months for EN,2 while median survival was 15.81 months and 18.42 months, respectively. The budgetary impact of these products to payers depends, in part, upon real world treatment duration and the proportion of mCRPC patients utilizing each product.
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Cost Analysis of Bortezomib Retreatment Compared with Switching to Carfilzomib in Patients with Relapsed Multiple Myeloma Previously Treated with Bortezomib
By
Abbie Ba-Mancini, MBA
;
Mei Sheng Duh, MPH, ScD
;
Jonathan Gravel, MS
;
Kevin B. Knopf, MD, MPH
;
Marie-Hélène Lafeuille, MA
;
Patrick Lefebvre, MA
;
Esprit Ma, MPH
;
Liviu Niculescu, MD
March 2013, Vol 4, No 3
Background:
In an era of multiple effective treatment options for relapsed/refractory multiple myeloma (MM), a recent meta-analysis has shown that retreatment with bortezomib continues to be an effective option in previously treated patients who relapsed.
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Imatinib Can Still Be Used as 1st-Line for Treating Chronic Myelogenous Leukemia
By
Wesley Wong, PhD
March 2013, Vol 4, No 3
Background:
The introduction of tyrosine kinase inhibitors (TKIs) into clinical practice resulted in a very dramatic prolongation of survival for most, but not all patients with chronic myeloid leukemia (CML) in chronic phase. If properly managed, and if adherence is greater than 80%, the 10-year survival rate reaches 85% for patients treated with the 1st-generation (Gen) TKI, imatinib (Gleevec).
Read More
Wait Time and Patient Satisfaction—Improving Outcomes Can Be as Easy as Child’s Play
By
Ann Bredensteiner
;
Julia Whiteker
March 2013, Vol 4, No 3
Background:
Breast Care at IU Health North Hospital is a multidisciplinary clinic comprised of breast surgeons, medical and radiation oncologists, plastic surgeons and geneticists. It has consistently achieved excellent patient satisfaction scores; however, one area needing improvement was in office wait time.
Read More
Say Ahh! Making Sense of Oral Assessments for Mucositis
By
Joan Collela, RN, DNP, APN-BC
;
Claudia Douglas, RN, MA, CNN
;
Joanne Growney, RN, MA, ANP-BC
;
Rebecca Martin, BSN, RN, OCN
;
Phyllis McKiernan, RN, MSN, APN-BC
March 2013, Vol 4, No 3
Background:
Chemotherapy and radiation therapy, the mainstays of current cancer treatment, often result in devastating side effects involving the oral cavity. Mucositis, an inflammatory and/or ulcerative lesion of the oral and/or gastrointestinal tract is a common therapy-related toxicity. Mucositis significantly impacts patients’ overall physical and functional well-being, as well as quality of life. There is strong evidence suggesting that the implementation of preventive strategy, such as patient and family education on the importance of oral hygiene practices, can lower the incidence of mucositis.
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Impact of Granulocyte Colony-Stimulating Factor and Treatment Modification on Eribulin Mesylate Therapy in Metastatic Breast Cancer Patients with Neutropenia
By
Faria C
;
Craver C
;
Yardley D
;
Cox D
;
Belk K
March 2013, Vol 4, No 3
Background:
Eribulin mesylate (EM) is a microtubule inhibitor shown to improve survival in patients with metastatic breast cancer (MBC) who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease.
Read More
Impact of Treatment Modification on Treatment Duration in Metastatic Breast Cancer Patients Treated with Eribulin Mesylate
March 2013, Vol 4, No 3
EM is a microtubule inhibitor shown to improve overall survival in metastatic breast cancer patients who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. There are side effects of EM, including neutropenia, anemia, asthenia/fatigue, alopecia, peripheral neuropathy, nausea, and constipation.
Read More
An Assessment of Racial Differences in Toxicities and Supportive Care in Patients with Metastatic Breast Cancer (MBC)
By
Nancy Beegle
;
Sibel Blau, MD
;
Claudio Faria
;
Traci Kalberer
;
Zhixiao Wang
March 2013, Vol 4, No 3
Background:
Racial disparities in clinical outcomes between Caucasian and African American (AA) MBC patients have been identified. Some of these disparities may be attributed to differences in toxicities and access to supportive care interventions.
Read More
Onyx Pharmaceuticals 360™: A Support Program for Patients with Multiple Myeloma and Their Caregivers
By
Joanne Buzaglo, PhD
;
Vicki Kennedy, LCSW
;
Jennifer Sharretts, MBA
March 2013, Vol 4, No 3
Background:
In 2007, the Institute of Medicine’s
Cancer Care for the Whole Patient: Meeting Psychosocial Health Needs
outlined a framework to integrate psychosocial health services into routine care for patients with cancer.
Read More
Ochsner CEO Calls for Adding Value in Healthcare
By
Caroline Helwick
Health Policy
,
Policies & Guidelines
March 2013, Vol 4, No 3
New Orleans, LA—“We must start to think differently if we want to change the healthcare system,” said Ochsner Health System President and CEO Warner L. Thomas, CPA, MBA, FACHE, in a keynote address at the 2013 Health Information and Management Systems Society (HIMSS) annual conference.
Read More
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Home
Issues
Online First
Issue Archive
Special Issues
Browse By Topic
Personalized Medicine
Economics & Value
FDA Approvals, News & Updates
COVID-19
Cholangiocarcinoma
View All Topics ›
Conference Correspondent
ESMO 2025 - Wrap-Up: Triple-Negative Breast Cancer
ASCO 2025 - Wrap-Up: Triple-Negative Breast Cancer
Web Exclusives
Web Exclusive Articles
Videos
Interview with the Innovators
Prostate Cancer Diagnostics Monthly Minutes
Webinars
Quick Quiz
Press Releases
Association for Value-Based Cancer Care
Value-Based Care in Myeloma