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Issues
2017
April 2017, Vol 8, No 2
April 2017, Vol 8, No 2
Hair Preservation Improved by 50% with Investigational Scalp-Cooling Device
By
Charles Bankhead
Breast Cancer
,
Solid Tumors
,
Personalized Medicine
April 2017, Vol 8, No 2
San Antonio, TX—The use of an investigational electronic scalp-cooling device in patients with breast cancer who had received alopecia-inducing chemotherapy resulted in reduced or no hair loss in 50% of the patients, according to results of a randomized clinical trial reported at the 2016 San Antonio Breast Cancer Symposium. By contrast, no patient in the control group had hair preservation.
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Good News for a Different Type of CDK4/CDK6 Inhibitor in Early Breast Cancer
By
Phoebe Starr
Breast Cancer
,
Solid Tumors
,
Personalized Medicine
April 2017, Vol 8, No 2
San Antonio, TX—Neoadjuvant therapy with the investigative CDK4/CDK6 inhibitor abemaciclib, alone or in combination with anastrozole (Arimidex), showed promising activity in postmenopausal hormone receptor (HR)-positive, HER2-negative breast cancer enrolled in the phase 2 NeoMONARCH study. Correlative tissue studies demonstrated that abemaciclib inhibited cell-cycle proliferation and activated the immune system, supporting its anticancer activity. Abemaciclib received a breakthrough therapy designation in 2015 as monotherapy for the treatment of patients with refractory HR-positive advanced breast cancer in heavily pretreated patients.
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FDA News - April 2017
FDA Approvals, News & Updates
April 2017, Vol 8, No 2
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Adding Everolimus to Antiestrogen Therapy Doubles Progression-Free Survival in Advanced Breast Cancer
By
Charles Bankhead
Breast Cancer
,
Solid Tumors
,
Personalized Medicine
April 2017, Vol 8, No 2
San Antonio, TX—The addition of the mTOR inhibitor everolimus (Afinitor) to the antiestrogen chemotherapy fulvestrant (Faslodex) led to a 2-fold increase in progression-free survival (PFS) in patients with advanced hormone receptor (HR)-positive breast cancer compared with fulvestrant alone, according to results of a randomized clinical trial presented at the 2016 San Antonio Breast Cancer Symposium.
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Leveraging Financial Advocates to Improve Patient Care
By
Meg Barbor, MPH
Value in Oncology
April 2017, Vol 8, No 2
St Louis, MO—Financial counselors can help patients find assistance with the often-prohibitive costs of cancer treatment. According to Jordan Karwedsky, a financial counselor at HSHS St Vincent Regional Cancer Center and Green Bay Oncology, Green Bay, WI, patients at these organizations saved more than $1 million on intravenous and oral chemotherapy in 2015 through copay assistance.
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Nivolumab May Be a New Treatment Option for Patients with Advanced Gastric Cancer, Experts Suggest
GI Cancers Symposium
April 2017, Vol 8, No 2
San Francisco, CA—Nivolumab (Opdivo) as salvage treatment significantly reduced the risk for death after second-line or later chemotherapy in patients with advanced gastric or gastroesophageal junction cancer. In a double-blind, randomized phase 3 trial, the median overall survival was improved by 37% in patients assigned to nivolumab versus placebo after previous treatment with at least 2 regimens, reported Yoon-Koo Kang, MD, PhD, Department of Oncology, Asan Medical Center, Seoul, South Korea, at the 2017 Gastrointestinal Cancers Symposium.
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Shifting Targets for Providers, Payers, and Patients with Cancer: Perspectives in Healthcare Reform
By
Gail Thompson
Value in Oncology
April 2017, Vol 8, No 2
Las Vegas, NV—A panel discussion at the 2017 Cancer Center Business Summit revealed continuing gaps in the evolution of healthcare reform among providers, payers, and patients with cancer. Michael Kolodziej, MD, National Medical Director, Managed Care Strategy, Flatiron Health, New York, NY—an oncologist with experience on the provider and the payer sides—moderated the panel discussion, which offered perspectives from the trenches on healthcare reform.
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Home
Issues
Online First
Latest Issue
Issue Archive
Special Issues
Browse By Topic
Personalized Medicine
Economics & Value
FDA Approvals, News & Updates
COVID-19
Cholangiocarcinoma
View All Topics ›
Conference Correspondent
SABCS 2023 - HER2+ MBC
ASCO 2023 - Breast Cancer
Web Exclusives
Web Exclusive Articles
Videos
Interview with the Innovators
Prostate Cancer Diagnostics Monthly Minutes
Webinars
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Press Releases
AVBCC
Association for Value-Based Cancer Care
VBCM
Value-Based Care in Myeloma