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Issues
2013
February 2013, Vol 4, No 2
February 2013, Vol 4, No 2
Women with Triple-Negative Breast Cancer Very Likely to Carry BRCA1 Gene
By
Phoebe Starr
Personalized Medicine
February 2013, Vol 4, No 2
San Antonio, TX—Triple-negative breast cancer (TNBC) was strongly associated with
BRCA1
status, but not with
BRCA2
status, in a large study of medically insured women. The study showed that the number of patients with
BRCA
mutations with a TNBC profile is statistically significant.
Read Article
A New Multigene Score Identifies Women with ER-Positive Breast Cancer at Risk for Late Metastases
By
Phoebe Starr
Personalized Medicine
February 2013, Vol 4, No 2
San Antonio, TX—A multigene score called EndoPredict can help to identify women with estrogen receptor (ER)-positive/HER2-negative breast cancer who are likely to develop metastatic disease in the long-term.
Read Article
Molecular Assays Reclassify Early Breast Cancer Type
By
Phoebe Starr
Breast Cancer
,
Personalized Medicine
February 2013, Vol 4, No 2
San Antonio, TX—Molecular subtyping of early breast cancers using MammaPrint and BluePrint assays allows the precise and accurate prediction of the molecular phenotype of the disease, which has the potential to guide the selection of personalized therapy if the tests are used prospectively.
Read Article
The Importance of Prioritizing Palliative Care in Oncology: How Payers Can Assist Providers
By
Rhonda Greenapple, MSPH, Reimbursement Intelligence
;
Ellen Licking
;
John Whang, MD, FACC,
Palliative Care
,
VBCC Perspectives
February 2013, Vol 4, No 2
Too often, palliative care, which was officially recognized as a medical specialty in 2006, is mistakenly thought to be synonymous with hospice care. Although palliative care includes the coordination of care for patients at the end of their lives, it more broadly aims to reduce patient suffering and is available to all patients with serious disease.
Read Article
Most Women Not Willing to Pay for Genetic Breast Cancer Testing
By
Caroline Helwick
Economics & Value
,
Health Economics
February 2013, Vol 4, No 2
Direct-to-consumer (DTC) genetic testing using single nucleotide polymorphisms (SNPs) is of interest to women who are concerned about breast cancer; however, these women are unwilling to pay the current costs, researchers from the Department of Surgery and Institute for Health Policy Studies, University of California, San Francisco (UCSF), Medical Center, reported at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.
Read Article
Costs of Second-Line Metastatic Colorectal Cancer Treatments Compared
By
Caroline Helwick
Economics & Value
,
Health Economics
February 2013, Vol 4, No 2
San Francisco, CA—For the second- line treatment of patients with metastatic colorectal cancer (CRC), the total costs were 14% lower with bevacizumab (Avastin) than with cetuximab (Erbitux), according to an analysis presented at the 2013 Gastrointestinal Cancers Symposium.
Read Article
Mayo Clinic Researchers Propose Screening Algorithm for HER2 in Patients with Esophageal Cancer
By
Caroline Helwick
GI Cancers Symposium
February 2013, Vol 4, No 2
The preferred screening test for human epidermal growth factor receptor (HER)2 status in surgical esophageal adenocarcinoma specimens is immunohistochemistry (IHC), with fluorescence in situ hybridization (FISH) restricted to cases with an indeterminate (2+) IHC score, according to investigators from the Mayo Clinic, Rochester, MN, who proposed a testing algorithm at the 2013 Gastrointestinal Cancers Symposium.
Read Article
In Patients with Colon Cancer, Genomic Classifiers Aid in Prognosis
By
Caroline Helwick
GI Cancers Symposium
February 2013, Vol 4, No 2
San Francisco, CA—Genomic classifiers—in particular, ColoPrint and MSI-Print, best when combined—can identify high-risk subsets among patients with surgically resected stage II and stage III colon cancers, reported researchers from M.D. Anderson Cancer Center at the 2013 Gastrointestinal Cancers Symposium.
Read Article
New Antibody Targeting VEGF Receptor-2 Extends Survival in Advanced Gastric Cancer
By
Mark Knight
GI Cancers Symposium
February 2013, Vol 4, No 2
San Francisco, CA—Ramucirumab as a second-line therapy extended overall and progression-free survival in a phase 3 clinical trial of patients with metastatic gastric cancer, said Charles S. Fuchs, MD, MPH, Director of the Center for Gastrointestinal Cancer at Dana-Farber Cancer Institute, Boston, and Professor of Medicine at Harvard Medical School, at the 2013 Gastrointestinal Cancers Symposium.
Read Article
In First-Line Metastatic CRC, Outcomes Comparable for Panitumumab and Bevacizumab
By
Audrey Andrews
GI Cancers Symposium
February 2013, Vol 4, No 2
San Francisco, CA—A randomized phase 2 study that compared panitumumab (Vectibix) and bevacizumab (Avastin) in the first-line treatment of metastatic colorectal cancer (CRC) showed these drugs to be similar in terms of progression-free survival (PFS) and overall survival (OS) benefits.
Read Article
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Home
Issues
Online First
Latest Issue
Issue Archive
Special Issues
Browse By Topic
Personalized Medicine
Economics & Value
FDA Approvals, News & Updates
COVID-19
Cholangiocarcinoma
View All Topics ›
Conference Correspondent
SABCS 2023 - HER2+ MBC
ASCO 2023 - Breast Cancer
Web Exclusives
Web Exclusive Articles
Videos
Interview with the Innovators
Prostate Cancer Diagnostics Monthly Minutes
Webinars
Quick Quizzes
Press Releases
AVBCC
Association for Value-Based Cancer Care
VBCM
Value-Based Care in Myeloma