Researchers Discover 2 Molecules Involved in Cancer Metastasis

June 2011, Vol 2, No 3 - Value Propositions


Researchers from Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, identified 2 regulatory molecules that enable a tumor, which originally is usually not deadly, to metastasize. This discovery could eventually help develop new therapies for the prevention of metastasis by inactivating these molecules.

The 2 molecules, p190RhoGEF and p190RhoGAP, “regulate the activity of RhoC, an enzyme that plays a crucial role during tumor metastasis and that has been identified as a biomarker for invasive breast cancer,” according to a press release from the university (April 7, 2011).