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WCLC 2016 – Lung Cancer
WCLC 2016 – Lung Cancer
Plenary Session 2B: Tobacco Control and Smoking Cessation and Prevention
WCLC 2016 – Lung Cancer
Conference Correspondent
Tobacco use is a preventable cause of cancer. Data suggest that approximately 33% of all cancers, including lung, head and neck, esophageal, pancreas, colon, and some types of leukemia, are caused by tobacco use. This session will review the relationships between smoking, free trade, industry regulation, and global public health.
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Mini Oral Session 1: Improvement and Implementation of Lung Cancer Screening
WCLC 2016 – Lung Cancer
Conference Correspondent
Early detection of lung cancer enhances patient survival. However, the value of specific screening programs is affected by multiple factors, including patient selection methods, triage algorithms, and imaging technology. This oral session includes presentations of novel approaches to the detection of lung cancer.
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Plenary Session 4A: Advances in Therapy for Metastatic Non–Small-Cell Lung Cancer (NSCLC)
WCLC 2016 – Lung Cancer
Conference Correspondent
This plenary session includes 4 presentations that describe the role of PD-L1 testing and immuno-oncology agents in the treatment of patients with first-line and relapsed NSCLC. All of these abstracts are embargoed until December 7, 2016.
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Plenary Session 5: Reflections from Giants on Milestones in the Treatment Advances in Lung Cancer—Translational Lung Cancer Research
WCLC 2016 – Lung Cancer
Conference Correspondent
Association of a survival benefit with chemotherapy use for non–small-cell lung cancer (NSCLC) was observed only after the development of cisplatin and platinum doublets. Recent therapeutic advancements in NSCLC and other solid tumors have revolved around the development of immunotherapies that inhibit immune checkpoints, as well as drugs that target driver mutations.
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First-Line Nivolumab Monotherapy and Nivolumab plus Ipilimumab in Patients with Advanced NSCLC (CheckMate 012)
WCLC 2016 – Lung Cancer
Conference Correspondent
Nivolumab, a PD-1 immune checkpoint inhibitor, has demonstrated superior efficacy relative to docetaxel in patients with advanced non–small-cell lung cancer (NSCLC) who progressed on or after platinum-based chemotherapy regardless of PD-L1 expression. Researchers presented findings from a phase 1 study of nivolumab as first-line therapy for advanced NSCLC.
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Pembrolizumab in Patients with Extensive-Stage Small-Cell Lung Cancer (SCLC): KEYNOTE-028
WCLC 2016 – Lung Cancer
Conference Correspondent
Extensive-stage disease (ED) small-cell lung cancer (SCLC) is characterized by limited treatment options and poor survival after platinum-based chemotherapy. Pembrolizumab, an inhibitor of PD-1, is active and safe in multiple solid tumors. Researchers presented updated safety and efficacy data for patients with ED SCLC who enrolled in KEYNOTE-028.
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Atezolizumab as First-Line Therapy for Advanced NSCLC in PD-L1–Selected Patients (BIRCH)
WCLC 2016 – Lung Cancer
Conference Correspondent
Atezolizumab, a humanized anti–PD-L1 monoclonal antibody, is being assessed in a phase 2 study in PD-L1–selected advanced non–small-cell lung cancer (NSCLC) patients. Initial analysis demonstrated a meaningful objective response rate with durable response in chemotherapy-naive first-line and relapsed PD-L1–selected patients. Researchers reported updated efficacy data in these first-line patients.
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Cost-Effectiveness Comparison of Screening Options for Lung Cancer Based on Randomized Population Trials
WCLC 2016 – Lung Cancer
Conference Correspondent
Based on data from the National Lung Screening Trial comparing lung cancer mortality associated with computed tomography (CT) and chest x-ray screening, CT screening is now standard clinical practice. However, questions about the value of CT screening remain given its cost and risk of false-positive results.
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Noninvasive Testing for Early-Stage Lung Cancer Chemoprevention Therapy
WCLC 2016 – Lung Cancer
Conference Correspondent
Rates of early detection of lung cancer remain poor. Identification of endobronchial lung dysplasia with a noninvasive sputum-based test could facilitate chemoprevention. Researchers evaluated a novel test for early-stage lung cancer to determine if it can identify tumor cells that have been exfoliated into sputum.
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Randomized Phase 3 Study of Osimertinib vs Platinum-Pemetrexed for Patients with EGFR T790M-Positive Advanced NSCLC After EGFR-TKI Therapy (AURA3)
WCLC 2016 – Lung Cancer
Conference Correspondent
Osimertinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), is indicated for use in patients with locally advanced or metastatic EGFR
T790M
-positive non–small-cell lung cancer (NSCLC) who have progressed on or after EGFR-TKI therapy. Researchers compared the efficacy and safety of osimertinib with platinum-based chemotherapy plus pemetrexed in this patient population.
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Home
Issues
Online First
Latest Issue
Issue Archive
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Browse By Topic
Personalized Medicine
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FDA Approvals, News & Updates
COVID-19
Cholangiocarcinoma
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Conference Correspondent
SABCS 2023 - HER2+ MBC
ASCO 2023 - Breast Cancer
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Prostate Cancer Diagnostics Monthly Minutes
Webinars
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Value-Based Care in Myeloma