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ASCO 2014
ASCO 2014 – Colorectal and Head & Neck Cancer
ASCO 2014 – Colorectal and Head & Neck Cancer
Impact of p16 Status on Cetuximab + Radiotherapy in Locally Advanced SCCHN
ASCO
,
ASCO 2014 – Colorectal and Head & Neck Cancer
Conference Correspondent
This was a retrospective analysis of the phase 3 IMCL-9815 trial assessing the role of HPV-p16 status in patients with locally advanced SCCHN receiving radiation therapy (RT) plus cetuximab (cetux) or RT alone (Rosenthal DI, et al. ASCO 2014. Abstract 6001).
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Chemoradiation or Cetuximab/Radiation Versus Induction Chemotherapy Followed by Chemoradiation in Locally Advanced SCCHN
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
Platinum-based chemoradiation therapy (CRT) is the current standard treatment for locally advanced SCCHN, and induction docetaxel/cisplatin/5-fluorouracil (TPF) is superior to cisplatin/5-fluorouracil alone, but it has not been tested when added to concomitant therapy.
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The E1308 Trial: Reduced-Dose IMRT in HPV-Associated OPSCC After Induction Chemotherapy
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
In the E2399 trial, HPV+ patients with oropharyngeal squamous cell carcinoma (OPSCC) attained 2-year overall survival (OS) of 95% and progression-free survival (PFS) of 86% when treated with induction chemotherapy (IC) and 70 Gy chemoradiation.
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RTOG 0522: The KRAS Variant and Response to Cetuximab
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
In many cancers,
KRAS
mutations can predict cancer risk, unique cancer biology, and response to certain therapeutic agents. RTOG 0522 was a phase 3 trial of cisplatin/radiation ± cetuximab for patients with locally advanced SCCHN, evaluating whether
KRAS
mutation status would predict the response to cetuximab in these patients (Weidhaas JB, et al. ASCO 2014. Abstract 6000).
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Adjuvant Lapatinib Plus Chemoradiation in High-Risk Patients with SCCHN
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
Read Article
Maintenance Strategies in mCRC After First-Line Therapy
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
Read Article
Final Results of the CAIRO3 Study
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
Read Article
Prognostic Impact of Deficient Mismatch Repair in CRC
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
Read Article
Preoperative Chemoradiotherapy and Postoperative Chemotherapy in Locally Advanced Rectal Cancer—Results of the CAO/ARO/AIO-04 Trial
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
Read Article
RAS Mutation Status and FOLFOX +/- Cetuximab—The OPUS Study
ASCO 2014 – Colorectal and Head & Neck Cancer
,
ASCO
Conference Correspondent
Read Article
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Home
Issues
Online First
Latest Issue
Issue Archive
Special Issues
Browse By Topic
Personalized Medicine
Economics & Value
FDA Approvals, News & Updates
COVID-19
Cholangiocarcinoma
View All Topics ›
Conference Correspondent
SABCS 2023 - HER2+ MBC
ASCO 2023 - Breast Cancer
Web Exclusives
Web Exclusive Articles
Videos
Interview with the Innovators
Prostate Cancer Diagnostics Monthly Minutes
Webinars
Quick Quizzes
Press Releases
AVBCC
Association for Value-Based Cancer Care
VBCM
Value-Based Care in Myeloma