Hematologic Malignancies

Value-Based Strategies for Patients with Multiple Myeloma

August 2015, Vol 6, No 7 - Multiple Myeloma

At the Fifth Annual Conference of the Association for Value-­Based Cancer Care in Washington, DC, Grant Lawless, RPh, MD, FACP, of the University of Southern California, Los Angeles, moderated a multidisciplinary panel on value-based care for patients with multiple myeloma. The panel included Gary Palmer, MD, JD, MBA, MPH, medical director of NantHealth, who highlighted the growing role of genomics testing in multiple myeloma, and Carol Ann Huff, MD, of the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, who discussed therapies in development for multiple myeloma, including novel monoclonal antibodies. The panelists outlined trends that are likely to affect costs and care patterns in multiple myeloma, including increasing use of triplet-drug regimens, maintenance therapy, and antibody-based therapies in development. [ Read More ]

Value of MRI in Smoldering Myeloma Stressed by the International Myeloma Working Group

Charles Bankhead

May 2015, Vol 6, No 4 - Multiple Myeloma

All patients with smoldering or asymptomatic multiple myeloma should undergo whole-body magnetic resonance imaging (MRI), or pelvic and spinal MRI if whole body is unavailable, according to recommendations from the International Myeloma Working Group (IMWG). The presence of >1 focal lesions >5 mm should be considered diagnostic for symptomatic myeloma requiring therapy. [ Read More ]

CHOP Disappearing as Standard of Care for Indolent NHL

Charles Bankhead

May 2013, Vol 4, No 4 - Hematologic Malignancies

A long-standing treatment standard for indolent non-Hodgkin lymphoma (NHL) has fallen victim to the chopping block, so to speak, at least in Germany.

The use of the cyclophosphamide (Cytoxan), doxorubicin (Adriamycin), vincristine (Oncovin), and prednisone (Deltasone; CHOP) regimen with or without rituximab (Rituxan; R-CHOP) has declined rapidly with the emergence of bendamustine (Treanda), which is used either alone or with ri­tuximab.

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