Value-Based Care in Myeloma

Value-Based Care in Myeloma

All-Oral Regimen May Become a New Standard of Care in Advanced Multiple Myeloma

Dana Taylor

February 2016, Vol 7, No 1 - Multiple Myeloma

With the recent FDA approval of the first oral proteasome inhibitor ixazomib (Ninlaro), patients with relapsed or refractory multiple myeloma who have received previous treatment now have access to an all-oral regimen. The FDA-indicated triplet regimen of ixazomib, lenalidomide (Revlimid), and dexamethasone (Decadron) significantly improved progression-free survival (PFS) compared with the doublet of lenalidomide and dexamethasone, reported Philippe Moreau, MD, University of Nantes, France, at ASH 2015. [ Read More ]

Value-Based Strategies for Patients with Multiple Myeloma

August 2015, Vol 6, No 7 - Multiple Myeloma

At the Fifth Annual Conference of the Association for Value-­Based Cancer Care in Washington, DC, Grant Lawless, RPh, MD, FACP, of the University of Southern California, Los Angeles, moderated a multidisciplinary panel on value-based care for patients with multiple myeloma. The panel included Gary Palmer, MD, JD, MBA, MPH, medical director of NantHealth, who highlighted the growing role of genomics testing in multiple myeloma, and Carol Ann Huff, MD, of the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, who discussed therapies in development for multiple myeloma, including novel monoclonal antibodies. The panelists outlined trends that are likely to affect costs and care patterns in multiple myeloma, including increasing use of triplet-drug regimens, maintenance therapy, and antibody-based therapies in development. [ Read More ]

Value of MRI in Smoldering Myeloma Stressed by the International Myeloma Working Group

Charles Bankhead

May 2015, Vol 6, No 4 - Multiple Myeloma

All patients with smoldering or asymptomatic multiple myeloma should undergo whole-body magnetic resonance imaging (MRI), or pelvic and spinal MRI if whole body is unavailable, according to recommendations from the International Myeloma Working Group (IMWG). The presence of >1 focal lesions >5 mm should be considered diagnostic for symptomatic myeloma requiring therapy. [ Read More ]