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Clinical Research
New Meta-Analysis: Complete Response to Neoadjuvant Therapy in Breast Cancer Predictor of Long-Term Benefit
By
Audrey Andrews
Clinical Research
,
Personalized Medicine
March 2013, Highlights
A new meta-analysis confirmed that patients with breast cancer who achieve a pathologic complete response (pCR) to neoadjuvant therapy have a more favorable outcome than those who do not.
Read Article
Evidence Still Cloudy for Anticancer Effects with Metformin
By
Caroline Helwick
Clinical Research
,
Personalized Medicine
March 2013, Highlights
Observational studies have suggested that the antidiabetes agent metformin (Glucophage) may have anticancer effects. New studies have attempted to confirm this, but the results and their meaning still remain unclear.
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More Evidence Links Vitamin D Deficiency to Worse Outcomes in Breast Cancer
By
Caroline Helwick
Clinical Research
,
Personalized Medicine
March 2013, Highlights
More evidence is accumulating that vitamin D levels play a role in breast cancer outcomes. Investigators from the United Kingdom reported that postmenopausal women with sufficient vitamin D levels were significantly less likely to develop bone metastases when taking zoledronic acid (Zometa) compared with women with lower vitamin D levels.
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Venlafaxine Lowers Endoxifen Levels, Reduces Tamoxifen Effectiveness
By
Caroline Helwick
Clinical Research
,
Personalized Medicine
March 2013, Highlights
The antidepressant venlafaxine (Effexor) is often prescribed to patients with breast cancer who are taking tamoxifen (Nolvadex) to help reduce the side effect of hot flashes. But according to research presented at the meeting, venlafaxine may reduce the effectiveness of tamoxifen.
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ASCO Shares Concerns Over the Future of Cancer Research
By
Colin Gittens
Clinical Research
,
Personalized Medicine
November/December 2010, Vol 1, No 6
Concerns about the future of cancer research exist among the spectrum of researchers and regulators, and in remarks prepared for the President’s Cancer Panel: The Future of Cancer Research—Accelerating Scientific Innovation (held September 22, 2010, in Boston), American Society of Clinical Oncology (ASCO) President
George W. Sledge, Jr, MD
, outlined some of the organization’s concerns regarding new biological therapies and the future of cancer research.
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Restoring Balance to the Cancer Research Regulation Equation
By
Colin Gittens
Clinical Research
,
Personalized Medicine
November/December 2010, Vol 1, No 6
Clinical cancer research is hampered by an overly complex and cautious regulatory system, which slows the development of lifesaving drugs, increases costs, and may be unethical, according to David J. Stewart,MD, of the University of Texas M.D. Anderson Cancer Center and colleagues (Stewart DJ, et al. Equipoise lost: ethics, costs, and the regulation of cancer clinical research. J Clin Oncol. 2010;28:2925-2935).
Read Article
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Home
Issues
Online First
Latest Issue
Issue Archive
Special Issues
Browse By Topic
Personalized Medicine
Economics & Value
FDA Approvals, News & Updates
COVID-19
Cholangiocarcinoma
View All Topics ›
Conference Correspondent
SABCS 2023 - HER2+ MBC
ASCO 2023 - Breast Cancer
Web Exclusives
Web Exclusive Articles
Videos
Interview with the Innovators
Prostate Cancer Diagnostics Monthly Minutes
Webinars
Quick Quizzes
Press Releases
AVBCC
Association for Value-Based Cancer Care
VBCM
Value-Based Care in Myeloma